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TREM2 Monoclonal Antibody [P2B5AT] (CPAB0560)

SKU:
CPAB0560
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG3
Clone:
P2B5AT
Applications:
WB
ELISA
  • TREM2 Monoclonal Antibody P2B5AT CPAB0560
  • TREM2 Monoclonal Antibody P2B5AT CPAB0560
€149
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Description

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TREM2 Monoclonal Antibody [P2B5AT] (CPAB0560)

The TREM2 Polyclonal Antibody (CPAB0560) is an essential tool for researchers studying TREM2, a transmembrane protein known for its role in regulating immune responses and inflammation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.TREM2, or triggering receptor expressed on myeloid cells 2, is a key player in the immune response, particularly in the brain where it is involved in microglial function and neuroinflammation.

Dysregulation of TREM2 has been linked to various neurodegenerative diseases, making it a promising target for therapeutic intervention.By utilizing the TREM2 Polyclonal Antibody, researchers can accurately detect and analyze TREM2 expression in different cell types, providing valuable insights into its functions and potential implications in disease pathology. This antibody is a valuable tool for studies focusing on neuroinflammation, neurodegenerative diseases, and immune system regulation.

Product Name:TREM2 Antibody
Product Sku:CPAB0560
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TREM2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TREM2 amino acids 19-161 purified from Ecoli.
Clone:P2B5AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:TREM2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG3
Background:TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. TREM2 may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in the TREM2 gene are a source of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Synonyms:Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM-2, TREM2, Trem2a, Trem2b, Trem2c.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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