The TREM1 Polyclonal Antibody (CAB16535) is a powerful tool for studying Triggering receptor expressed on myeloid cells 1 (TREM1), a key regulator of inflammatory responses. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting TREM1 protein in human samples, making it ideal for Western blot applications. TREM1 is a cell surface receptor that amplifies immune responses during inflammation, making it a promising target for research in immunology, sepsis, and inflammatory diseases. Understanding the role of TREM1 in regulating immune activation is crucial for developing therapeutic strategies to modulate immune responses in these conditions.
With its ability to specifically bind to TREM1, this polyclonal antibody enables precise detection and analysis of TREM1 in various cell types, offering valuable insights for researchers in the fields of immunology and inflammatory disorders. Explore the potential of TREM1 in immune modulation with the reliable performance of the TREM1 Polyclonal Antibody (CAB16535).
Product Name:
TREM1 Rabbit Polyclonal Antibody
SKU:
CAB16535
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human TREM1 (NP_061113.1).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
26kDa
Observed MW:
26kDa
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
54210
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TREM1 Rabbit pAb (CAB16535) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
