The TRDMT1 Polyclonal Antibody (CAB10535) is a valuable tool for researchers studying TRDMT1, a protein involved in RNA modification and epigenetic regulation. This antibody, raised in rabbits, exhibits high specificity and sensitivity in detecting TRDMT1 in various experimental contexts, such as Western blot analysis.TRDMT1, also known as tRNA aspartic acid methyltransferase 1, plays a crucial role in maintaining accurate protein synthesis by modifying tRNA molecules. Dysregulation of TRDMT1 has been linked to various diseases, including cancer and neurological disorders.
By investigating the expression and function of TRDMT1, researchers can gain insights into its potential role as a therapeutic target or diagnostic marker in these diseases.With its reliable performance and broad applicability in molecular biology and biomedical research, the TRDMT1 Polyclonal Antibody (CAB10535) is a valuable asset for advancing our understanding of TRDMT1 biology and its implications in human health and disease.
Product Name:
TRDMT1 Rabbit Polyclonal Antibody
SKU:
CAB10535
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 192-391 of human TRDMT1 (NP_004403.1).
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
Purification Method:
Affinity purification
Gene ID:
1787
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRDMT1 Rabbit pAb (CAB10535) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
