The TRBC1 Monoclonal Antibody (PACO30790) is a valuable tool for researchers studying T cell receptor beta constant 1 (TRBC1), a component of the T cell receptor complex involved in antigen recognition and immune response. This monoclonal antibody, produced using hybridoma technology, offers high specificity and sensitivity for detecting TRBC1 in human samples, making it ideal for applications such as flow cytometry and immunohistochemistry.TRBC1 is essential for the function of T cells in adaptive immunity, playing a key role in the recognition and response to foreign antigens.
Abnormalities in TRBC1 expression or function have been linked to immune disorders, autoimmune diseases, and cancer, underscoring the importance of studying this molecule in various research settings. The TRBC1 Monoclonal Antibody enables accurate detection and analysis of TRBC1, facilitating investigations into the role of T cell receptors in disease pathogenesis and therapeutic targeting.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO30790 at dilution of 1:100.
Immunofluorescent analysis of MCF-7 cells using PACO30790 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO30790 at dilution of 1:100.
Synonyms:
T-cell receptor beta-1 chain C region, TRBC1
UniProt Protein Function:
TRBC1: Protein type: Receptor, misc.; Membrane protein, integralChromosomal Location of Human Ortholog: 7q34Cellular Component: integral to membrane; membrane; plasma membraneBiological Process: immune response; regulation of immune response; T cell costimulation; T cell receptor signaling pathway