TRAT1 Antibody (PACO37162)
- SKU:
- PACO37162
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TRAT1 Antibody (PACO37162)
The TRAT1 Polyclonal Antibody (PACO37162) is a powerful tool for researchers studying TRAT1, a crucial protein involved in T cell receptor signaling. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot and immunohistochemistry applications. By targeting TRAT1, researchers can effectively investigate its role in T cell activation and immune system function.TRAT1, also known as T cell receptor associated transmembrane adaptor 1, plays a vital role in T cell receptor signaling, which is essential for initiating immune responses. By studying TRAT1, researchers can gain valuable insights into how T cells communicate and respond to antigens, paving the way for the development of novel immunotherapies and treatments for immune-related disorders.
The TRAT1 Polyclonal Antibody (PACO37162) offers researchers a reliable tool for detecting and studying TRAT1 in various cell types and tissues, allowing for a deeper understanding of its function in immune responses. With its high specificity and sensitivity, this antibody is a valuable asset for researchers investigating T cell receptor signaling pathways and their implications in health and disease.
| Antibody Name: | TRAT1 Antibody (PACO37162) |
| Antibody SKU: | PACO37162 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human T-cell receptor-associated transmembrane adapter 1 protein (29-186AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO37162 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human thymus tissue using PACO37162 at dilution of 1:100. |
| Background: | Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. |
| Synonyms: | T-cell receptor-associated transmembrane adapter 1 (T-cell receptor-interacting molecule) (TRIM) (pp29/30), TRAT1, TCRIM |
| UniProt Protein Function: | TRAT1: Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q13 Cellular Component: integral to plasma membrane; plasma membrane; T cell receptor complex Molecular Function:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; transmembrane receptor protein tyrosine kinase adaptor protein activity Biological Process: cellular defense response; negative regulation of receptor recycling; negative regulation of transport; phosphoinositide-mediated signaling; positive regulation of calcium-mediated signaling; positive regulation of T cell receptor signaling pathway; regulation of phosphoinositide 3-kinase cascade; signal transduction; T cell receptor signaling pathway |
| UniProt Code: | Q6PIZ9 |
| NCBI GenInfo Identifier: | 74749223 |
| NCBI Gene ID: | 50852 |
| NCBI Accession: | Q6PIZ9.1 |
| UniProt Secondary Accession: | Q6PIZ9,Q9NZX5, |
| UniProt Related Accession: | Q6PIZ9 |
| Molecular Weight: | 21,211 Da |
| NCBI Full Name: | T-cell receptor-associated transmembrane adapter 1 |
| NCBI Synonym Full Names: | T cell receptor associated transmembrane adaptor 1 |
| NCBI Official Symbol: | TRAT1Â Â |
| NCBI Official Synonym Symbols: | TRIM; TCRIM; HSPC062; pp29/30Â Â |
| NCBI Protein Information: | T-cell receptor-associated transmembrane adapter 1 |
| UniProt Protein Name: | T-cell receptor-associated transmembrane adapter 1 |
| UniProt Synonym Protein Names: | T-cell receptor-interacting molecule; TRIM; pp29/30 |
| Protein Family: | T-cell receptor-associated transmembrane adapter |
| UniProt Gene Name: | TRAT1Â Â |
| UniProt Entry Name: | TRAT1_HUMAN |
| Antibodies |
| TRAT1 Antibody (PACO12897) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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