TRAT1 Antibody (PACO12897)
- SKU:
- PACO12897
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TRAT1 Antibody (PACO12897)
The TRAT1 Polyclonal Antibody (PAC012897) is a valuable tool for researchers studying TRAT1, a key protein involved in T cell receptor signaling pathways. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to TRAT1, this antibody enables the detection and analysis of TRAT1 protein expression in various cell types, making it an essential tool for immunology and cancer research studies.TRAT1, also known as TCR-associated transmembrane adaptor protein 1, plays a crucial role in T cell receptor signaling by facilitating the recruitment of important signaling molecules.
Its involvement in T cell activation and response regulation makes it a promising target for research on diseases such as cancer, autoimmune disorders, and immunodeficiencies. Understanding the function of TRAT1 is vital for developing targeted therapies that modulate T cell signaling pathways in the context of these diseases. Overall, the TRAT1 Polyclonal Antibody (PAC012897) offers researchers a reliable and specific tool for studying TRAT1 protein expression and function, providing valuable insights into T cell receptor signaling and its implications in various disease states.
| Antibody Name: | TRAT1 Antibody (PACO12897) |
| Antibody SKU: | PACO12897 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human TRAT1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | T cell receptor associated transmembrane adaptor 1;TRAT1;HSPC062;TCRIM;TRIM ; |
| UniProt Protein Function: | TRAT1: Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q13 Cellular Component: integral to plasma membrane; plasma membrane; T cell receptor complex Molecular Function:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; transmembrane receptor protein tyrosine kinase adaptor protein activity Biological Process: cellular defense response; negative regulation of receptor recycling; negative regulation of transport; phosphoinositide-mediated signaling; positive regulation of calcium-mediated signaling; positive regulation of T cell receptor signaling pathway; regulation of phosphoinositide 3-kinase cascade; signal transduction; T cell receptor signaling pathway |
| UniProt Code: | Q6PIZ9 |
| NCBI GenInfo Identifier: | 74749223 |
| NCBI Gene ID: | 50852 |
| NCBI Accession: | Q6PIZ9.1 |
| UniProt Secondary Accession: | Q6PIZ9,Q9NZX5, |
| UniProt Related Accession: | Q6PIZ9 |
| Molecular Weight: | 21,211 Da |
| NCBI Full Name: | T-cell receptor-associated transmembrane adapter 1 |
| NCBI Synonym Full Names: | T cell receptor associated transmembrane adaptor 1 |
| NCBI Official Symbol: | TRAT1Â Â |
| NCBI Official Synonym Symbols: | TRIM; TCRIM; HSPC062; pp29/30Â Â |
| NCBI Protein Information: | T-cell receptor-associated transmembrane adapter 1 |
| UniProt Protein Name: | T-cell receptor-associated transmembrane adapter 1 |
| UniProt Synonym Protein Names: | T-cell receptor-interacting molecule; TRIM; pp29/30 |
| Protein Family: | T-cell receptor-associated transmembrane adapter |
| UniProt Gene Name: | TRAT1Â Â |
| UniProt Entry Name: | TRAT1_HUMAN |
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