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TRAT1 Antibody (PACO12897)

SKU:
PACO12897
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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TRAT1 Antibody (PACO12897)

The TRAT1 Polyclonal Antibody (PAC012897) is a valuable tool for researchers studying TRAT1, a key protein involved in T cell receptor signaling pathways. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to TRAT1, this antibody enables the detection and analysis of TRAT1 protein expression in various cell types, making it an essential tool for immunology and cancer research studies.TRAT1, also known as TCR-associated transmembrane adaptor protein 1, plays a crucial role in T cell receptor signaling by facilitating the recruitment of important signaling molecules.

Its involvement in T cell activation and response regulation makes it a promising target for research on diseases such as cancer, autoimmune disorders, and immunodeficiencies. Understanding the function of TRAT1 is vital for developing targeted therapies that modulate T cell signaling pathways in the context of these diseases. Overall, the TRAT1 Polyclonal Antibody (PAC012897) offers researchers a reliable and specific tool for studying TRAT1 protein expression and function, providing valuable insights into T cell receptor signaling and its implications in various disease states.

Antibody Name:TRAT1 Antibody (PACO12897)
Antibody SKU:PACO12897
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human TRAT1
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:T cell receptor associated transmembrane adaptor 1;TRAT1;HSPC062;TCRIM;TRIM ;
UniProt Protein Function:TRAT1: Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
UniProt Protein Details:

Protein type:Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q13

Cellular Component: integral to plasma membrane; plasma membrane; T cell receptor complex

Molecular Function:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; transmembrane receptor protein tyrosine kinase adaptor protein activity

Biological Process: cellular defense response; negative regulation of receptor recycling; negative regulation of transport; phosphoinositide-mediated signaling; positive regulation of calcium-mediated signaling; positive regulation of T cell receptor signaling pathway; regulation of phosphoinositide 3-kinase cascade; signal transduction; T cell receptor signaling pathway

UniProt Code:Q6PIZ9
NCBI GenInfo Identifier:74749223
NCBI Gene ID:50852
NCBI Accession:Q6PIZ9.1
UniProt Secondary Accession:Q6PIZ9,Q9NZX5,
UniProt Related Accession:Q6PIZ9
Molecular Weight:21,211 Da
NCBI Full Name:T-cell receptor-associated transmembrane adapter 1
NCBI Synonym Full Names:T cell receptor associated transmembrane adaptor 1
NCBI Official Symbol:TRAT1  
NCBI Official Synonym Symbols:TRIM; TCRIM; HSPC062; pp29/30  
NCBI Protein Information:T-cell receptor-associated transmembrane adapter 1
UniProt Protein Name:T-cell receptor-associated transmembrane adapter 1
UniProt Synonym Protein Names:T-cell receptor-interacting molecule; TRIM; pp29/30
Protein Family:T-cell receptor-associated transmembrane adapter
UniProt Gene Name:TRAT1  
UniProt Entry Name:TRAT1_HUMAN

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