The TRAPPC2 Polyclonal Antibody (CAB10465) is a valuable tool for research involving TRAPPC2, a subunit of the TRAPP complex that plays a key role in vesicle trafficking and protein transport within cells. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TRAPPC2 protein, this antibody enables researchers to detect and analyze TRAPPC2 expression in various cell types, making it ideal for studies in cell biology and molecular biology.TRAPPC2 is essential for maintaining the integrity of the Golgi apparatus and facilitating protein trafficking between different cellular compartments.
Dysregulation of TRAPPC2 function has been linked to various cellular processes, including autophagy, cell signaling, and proliferation. Research into TRAPPC2 can provide insights into these fundamental cellular processes and may have implications for understanding diseases related to protein trafficking defects, such as neurodegenerative disorders and metabolic syndromes.By using the TRAPPC2 Polyclonal Antibody (CAB10465), researchers can further explore the functions and mechanisms of TRAPPC2 in cellular processes, aiding in the development of targeted therapies and treatments for diseases associated with protein trafficking abnormalities.
Product Name:
TRAPPC2 Rabbit Polyclonal Antibody
SKU:
CAB10465
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TRAPPC2 (NP_055378.1).
The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6399
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TRAPPC2 antibody (CAB10465) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
