The Transferrin Rabbit Monoclonal Antibody (CAB19130) is a high-quality antibody designed for research involving Transferrin, a key protein involved in iron transport and homeostasis. This antibody, generated using rabbit monoclonal technology, demonstrates high specificity and sensitivity for detecting Transferrin in a variety of samples.Transferrin plays a crucial role in the binding and transport of iron in the blood, making it essential for numerous physiological processes such as erythropoiesis and cellular growth. Dysregulation of Transferrin expression has been implicated in various diseases, including iron overload disorders and certain types of cancer.This antibody is validated for use in techniques such as Western blotting and immunohistochemistry, making it a versatile tool for researchers studying Transferrin in both basic science and clinical settings.
Its ability to detect and analyze Transferrin protein levels in different cell types and tissues makes it ideal for investigations into iron metabolism, cell growth, and disease pathogenesis related to iron dysregulation. By utilizing the Transferrin Rabbit Monoclonal Antibody (CAB19130), researchers can gain valuable insights into the role of Transferrin in health and disease, ultimately contributing to the development of new therapies and diagnostic tools in fields such as hematology, oncology, and metabolic disorders.
Product Name:
Transferrin Rabbit Monoclonal Antibody
SKU:
CAB19130
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Transferrin (P02787).
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
Purification Method:
Affinity purification
Gene ID:
7018
Clone Number:
ARC0338
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Human serum, using Transferrin Rabbit mAb (CAB19130) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
