The Transcobalamin-1 Polyclonal Antibody (CAB6414) is a crucial tool for researchers studying Transcobalamin-1, a protein involved in vitamin B12 transport and metabolism. This antibody is produced in rabbits and has been validated for Western blot applications, making it a reliable choice for detecting and analyzing Transcobalamin-1 in various samples.Transcobalamin-1, also known as TCN1, is essential for the uptake and transport of vitamin B12, which is crucial for multiple biological processes, including DNA synthesis and nerve function. Dysregulation of Transcobalamin-1 has been linked to vitamin B12 deficiency and various health conditions, making it a promising target for further investigation in the fields of nutrition, metabolism, and neurology.
By using the Transcobalamin-1 Polyclonal Antibody, researchers can explore the role of Transcobalamin-1 in health and disease, leading to a better understanding of vitamin B12 metabolism and potential therapeutic interventions. This antibody is a valuable asset for studies focusing on nutrition, metabolic disorders, and neurological diseases related to vitamin B12 deficiency.
Product Name:
TCN1 Rabbit Polyclonal Antibody
SKU:
CAB6414
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2).
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
Purification Method:
Affinity purification
Gene ID:
6947
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TCN1 Rabbit pAb (CAB6414) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
