The TRIM1 Polyclonal Antibody (CAB15142) is a valuable tool for researchers studying TRIM1, a protein involved in regulating various cellular processes, including cell growth and differentiation. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.TRIM1, also known as tripartite motif-containing protein 1, plays a crucial role in maintaining cellular homeostasis by regulating protein degradation and turnover. Dysregulation of TRIM1 has been implicated in various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
By specifically binding to TRIM1, this antibody enables researchers to detect and analyze the protein in different cell types, providing valuable insights into its function and potential implications in disease pathology. With its high specificity and sensitivity, the TRIM1 Polyclonal Antibody is an essential tool for advancing research in molecular biology and drug development.
Product Name:
TRAM1 Rabbit Polyclonal Antibody
SKU:
CAB15142
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 305-374 of human TRAM1 (NP_055109.1).
This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause.
Purification Method:
Affinity purification
Gene ID:
23471
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRAM1 Rabbit pAb (CAB15142) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
