The TRAF7 Polyclonal Antibody (CAB3095) is a valuable tool for researchers studying TRAF7, a key signaling protein involved in various cellular processes. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to TRAF7 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it an essential component for studies in cell signaling pathways and developmental biology.TRAF7, also known as TNF receptor-associated factor 7, is a crucial regulator of diverse cellular functions, including cell survival, proliferation, and immune response modulation.
Its involvement in signaling pathways makes it a potential target for research on diseases such as cancer, autoimmune disorders, and inflammatory conditions. Investigating the role of TRAF7 can provide insights into novel therapeutic strategies aimed at targeting these diseases by manipulating the signaling networks controlled by this protein.
Product Name:
TRAF7 Rabbit Polyclonal Antibody
SKU:
CAB3095
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 380-479 of human TRAF7 (NP_115647.2).
Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.
Purification Method:
Affinity purification
Gene ID:
84231
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRAF7 Rabbit pAb (CAB3095) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
