The TRAF7 Polyclonal Antibody (CAB15607) is a valuable tool for researchers studying TRAF7, a crucial protein involved in diverse cellular processes such as signaling pathways and protein regulation. This antibody, produced in rabbits, is highly specific to human samples and has been extensively validated for use in Western blot applications. By targeting the TRAF7 protein, this antibody enables the detection and analysis of TRAF7 expression in various cell types, making it ideal for studies in cell biology, signal transduction, and cancer research.TRAF7, also known as TNF receptor-associated factor 7, is a key regulator of numerous cellular activities, including cell proliferation, survival, and immune response.
Dysregulation of TRAF7 has been implicated in various diseases, such as cancer, inflammatory disorders, and neurodegenerative conditions, highlighting its importance in pathophysiology. Research into the functions and interactions of TRAF7 is essential for developing targeted therapies and understanding the underlying mechanisms of disease progression.Overall, the TRAF7 Polyclonal Antibody (CAB15607) offers researchers a reliable tool to explore the role of TRAF7 in cellular processes and disease pathways, advancing our understanding of critical biological functions and potential therapeutic targets.
Product Name:
TRAF7 Rabbit Polyclonal Antibody
SKU:
CAB15607
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 260-400 of human TRAF7 (NP_115647.2).
Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.
Purification Method:
Affinity purification
Gene ID:
84231
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRAF7 Rabbit pAb (CAB15607) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
