TRAF4 Rabbit Polyclonal Antibody (CAB7047)
- SKU:
- CAB7047
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | TRAF4 Rabbit Polyclonal Antibody |
SKU: | CAB7047 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 251-470 of human TRAF4 (NP_004286.2). |
Sequence: | PFKD SGCK HRCP KLAM ARHV EESV KPHL AMMC ALVS RQRQ ELQE LRRE LEEL SVGS DGVL IWKI GSYG RRLQ EAKA KPNL ECFS PAFY THKY GYKL QVSA FLNG NGSG EGTH LSLY IRVL PGAF DNLL EWPF ARRV TFSL LDQS DPGL AKPQ HVTE TFHP DPNW KNFQ KPGT WRGS LDES SLGF GYPK FISH QDIR KRNY VRDD AVFI RAAV ELPR KILS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CART1; MLN62; RNF83; TRAF4 |
Positive Sample: | MCF7,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus, Peripheral membrane protein, cytoskeleton, perinuclear region, tight junction. |
Calculated MW: | 54kDa |
Observed MW: | 54kDa |
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.
Purification Method: | Affinity purification |
Gene ID: | 9618 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |