TRAF4 Monoclonal Antibody (CAB22472)
- SKU:
- CAB22472
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | TRAF4 Monoclonal Antibody |
SKU: | CAB22472 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 209-470 of human TRAF4 (NP_004286.2). |
Sequence: | SHQY QCPR LPVA CPNQ CGVG TVAR EDLP GHLK DSCN TALV LCPF KDSG CKHR CPKL AMAR HVEE SVKP HLAM MCAL VSRQ RQEL QELR RELE ELSV GSDG VLIW KIGS YGRR LQEA KAKP NLEC FSPA FYTH KYGY KLQV SAFL NGNG SGEG THLS LYIR VLPG AFDN LLEW PFAR RVTF SLLD QSDP GLAK PQHV TETF HPDP NWKN FQKP GTWR GSLD ESSL GFGY PKFI SHQD IRKR NYVR DDAV FIRA AVEL PRKI LS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | CART1; MLN62; RNF83; TRAF4 |
Positive Sample: | MCF7,HeLa,NIH/3T3,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus, Peripheral membrane protein, cytoskeleton, perinuclear region, tight junction. |
Calculated MW: | 54kDa |
Observed MW: | 54kDa |
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.
Purification Method: | Affinity purification |
Gene ID: | 9618 |
Clone Number: | ARC57454 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |