TRAF3 Rabbit Polyclonal Antibody (CAB0875)
- SKU:
- CAB0875
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
Product Name: | TRAF3 Rabbit Polyclonal Antibody |
SKU: | CAB0875 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TRAF3 (NP_003291.2). |
Sequence: | MESS KKMD SPGA LQTN PPLK LHTD RSAG TPVF VPEQ GGYK EKFV KTVE DKYK CEKC HLVL CSPK QTEC GHRF CESC MAAL LSSS SPKC TACQ ESIV KDKV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:1000 |
Synonyms: | CAP1; LAP1; CAP-1; CRAF1; IIAE5; CD40bp; RNF118; TRAF3 |
Positive Sample: | 293T,Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endosome, Mitochondrion. |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5.
Purification Method: | Affinity purification |
Gene ID: | 7187 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |