TRADD Rabbit Polyclonal Antibody (CAB18626)
- SKU:
- CAB18626
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TRADD Rabbit Polyclonal Antibody |
SKU: | CAB18626 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-312 of human TRADD (NP_003780.1). |
Sequence: | QTFL FQGQ PVVN RPLS LKDQ QTFA RSVG LKWR KVGR SLQR GCRA LRDP ALDS LAYE YERE GLYE QAFQ LLRR FVQA EGRR ATLQ RLVE ALEE NELT SLAE DLLG LTDP NGGL A |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | Hs.89862; TRADD |
Positive Sample: | Mouse brain,Mouse spleen,Mouse kidney |
Cellular Localization: | Cytoplasm, Nucleus, cytoskeleton. |
Calculated MW: | 34kDa |
Observed MW: | 32kDa |
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Purification Method: | Affinity purification |
Gene ID: | 8717 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |