The TPTE2 Polyclonal Antibody (PACO37030) is a valuable tool for researchers studying TPTE2, a protein involved in various cellular processes, including immune regulation and signal transduction. This antibody, generated from rabbit immunizations, is highly specific for human samples and has been validated for use in Western blot applications.TPTE2, also known as transmembrane phosphatase with tensin homology (TPTE) domain-containing protein 2, is a key player in regulating immune responses and cellular signaling pathways. By targeting TPTE2 with this antibody, researchers can detect and analyze the protein in different cell types, providing valuable insights into its function and potential therapeutic applications.
Studies involving TPTE2 are particularly relevant in the fields of immunology and cancer research, as dysregulation of TPTE2 expression has been linked to autoimmune disorders, inflammatory diseases, and cancer progression. By investigating the role of TPTE2 in these conditions, researchers can uncover novel targets for drug development and personalized medicine approaches.Overall, the TPTE2 Polyclonal Antibody (PACO37030) offers researchers a reliable tool for studying TPTE2 in various biological contexts, ultimately advancing our understanding of immune regulation and disease pathology.
Antibody Name:
TPTE2 Antibody (PACO37030)
Antibody SKU:
PACO37030
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 protein (167-411AA)
TPTE2: 5 isoforms of the human protein are produced by alternative splicingProtein type: Membrane protein, multi-pass; EC 3.1.3.67; Phosphatase, lipid; Membrane protein, integralChromosomal Location of Human Ortholog: 13q12.11Cellular Component: endoplasmic reticulum membrane; Golgi membrane; integral to membraneMolecular Function: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activityBiological Process: phosphatidylinositol biosynthetic process; phospholipid metabolic process
UniProt Protein Details:
NCBI Summary:
TPIP is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.[supplied by OMIM, Jul 2002]
