The TPT1 Polyclonal Antibody (CAB5442) is a valuable tool for researchers studying TPT1, a protein involved in various cellular processes such as cell proliferation, differentiation, and apoptosis. This antibody, derived from rabbit serum, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the TPT1 protein, researchers can accurately detect and analyze its expression in a wide range of cell types.TPT1, also known as translationally controlled tumor protein, plays a crucial role in regulating cell growth and survival. Its dysregulation has been linked to cancer development and progression, making it a promising target for cancer research.
By studying the function of TPT1, researchers can gain valuable insights into the mechanisms underlying oncogenesis and potentially identify new therapeutic strategies for cancer treatment.Overall, the TPT1 Polyclonal Antibody (CAB5442) is a reliable tool for investigating the role of TPT1 in cellular processes and disease development, particularly in the field of cancer research. Its high specificity and sensitivity make it a valuable asset for researchers seeking to unravel the complexities of TPT1 biology.
Product Name:
TCTP/TPT1 Rabbit Polyclonal Antibody
SKU:
CAB5442
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TCTP/TCTP/TPT1 (NP_003286.1).
This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
7178
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TCTP/TCTP/TPT1 antibody (CAB5442) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
