The TPT1 Polyclonal Antibody (CAB13367) is a valuable tool for researchers studying TPT1, also known as translationally controlled tumor protein. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.TPT1 is a multifunctional protein involved in various cellular processes, including cell growth, proliferation, and survival. It has been implicated in cancer progression and is overexpressed in many cancer types, making it an attractive target for therapeutic interventions.
The TPT1 Polyclonal Antibody binds specifically to TPT1 protein, enabling researchers to detect and analyze its expression levels in different cell types.Understanding the role of TPT1 in cancer development and progression is essential for developing targeted therapies that can potentially inhibit its oncogenic effects. By using the TPT1 Polyclonal Antibody, researchers can further investigate the molecular mechanisms underlying TPT1 function and potentially discover novel therapeutic strategies for combating cancer.
Product Name:
TCTP/TPT1 Rabbit Polyclonal Antibody
SKU:
CAB13367
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TCTP/TCTP/TPT1 (NP_003286.1).
This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
7178
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TCTP/TCTP/TPT1 antibody (CAB13367) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
