The TPST2 Polyclonal Antibody (CAB18141) is a valuable tool for researchers studying TPST2, a key enzyme involved in the sulfation of tyrosine residues in proteins. This rabbit-raised antibody is highly specific to TPST2 in human samples and is suitable for use in Western blot applications. By targeting the TPST2 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for investigations in areas such as glycobiology and protein modification.TPST2 is known for its role in post-translational modification of proteins through tyrosine sulfation, which is crucial for their proper function in processes like cell adhesion and signaling.
Research on TPST2 is essential for understanding how tyrosine sulfation impacts protein interactions and function, making it a potential target for therapeutic interventions in diseases related to protein dysfunction or misregulation.By using the TPST2 Polyclonal Antibody, researchers can explore the intricacies of TPST2-mediated tyrosine sulfation and its implications in various cellular processes. This antibody is a reliable tool for advancing understanding of protein modification pathways and their potential therapeutic implications.
Product Name:
TPST2 Polyclonal Antibody
SKU:
CAB18141
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-370 of human TPST2 (NP_003586.3).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
42kDa
Observed MW:
42kDa
The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Alternative splicing produces multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
8459
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from U-2 OS cells using TPST2 Rabbit pAb (CAB18141) at 1:1000 dilution incubated overnight at 4°C.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020)Exposure time: 60 s.
