TPSD1 Antibody (PACO07265)
- SKU:
- PACO07265
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TPSD1 Antibody (PACO07265)
The TPSD1 Polyclonal Antibody (PACO07265) is a valuable tool for researchers studying TPSD1, a protein with potential implications in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically targets the TPSD1 protein, enabling accurate detection and analysis in a variety of cell types.TPSD1, also known as a potential tumor suppressor, is thought to play a role in regulating cell growth and proliferation.
Its involvement in these pathways suggests potential relevance in cancer research and other disease contexts. By investigating the function of TPSD1, researchers can gain insights into its potential as a therapeutic target or biomarker for various conditions.Overall, the TPSD1 Polyclonal Antibody offers researchers a reliable tool for studying the function and expression of TPSD1 in different biological contexts, making it a valuable asset for ongoing research efforts in the fields of cancer biology and molecular biology.
| Antibody Name: | TPSD1 Antibody (PACO07265) |
| Antibody SKU: | PACO07265 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:10000-1:20000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from Tryptase-3 at AA range: 51-100 |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200. |
 | Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200. |
 | Western Blot analysis of HEPG2 cells using Tryptase-3 Polyclonal Antibody diluted at 1:800. Secondary antibody was diluted at 1:20000. |
| Synonyms: | Tryptase delta (EC 3.4.21.59) (Delta-tryptase) (HmMCP-3-like tryptase III) (Mast cell mMCP-7-like) (Tryptase-3) |
| UniProt Protein Function: | TPSD1: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Belongs to the peptidase S1 family. Tryptase subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.21.59; Secreted, signal peptide; Secreted; Protease Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: extracellular region Molecular Function:serine-type peptidase activity; serine-type endopeptidase activity Biological Process: proteolysis |
| NCBI Summary: | Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BZJ3 |
| NCBI GenInfo Identifier: | 11321636 |
| NCBI Gene ID: | 23430 |
| NCBI Accession: | NP_036349.1 |
| UniProt Secondary Accession: | Q9BZJ3,O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8 |
| UniProt Related Accession: | Q9BZJ3 |
| Molecular Weight: | 26,584 Da |
| NCBI Full Name: | tryptase delta |
| NCBI Synonym Full Names: | tryptase delta 1 |
| NCBI Official Symbol: | TPSD1Â Â |
| NCBI Official Synonym Symbols: | MCP7L1; MMCP-7L; MCP7-LIKEÂ Â |
| NCBI Protein Information: | tryptase delta; tryptase-3; mMCP-7-like-1; mMCP-7-like-2; delta-tryptase; mast cell tryptase; hmMCP-3-like tryptase III; mMCP-7-like delta II tryptase |
| UniProt Protein Name: | Tryptase delta |
| UniProt Synonym Protein Names: | Delta-tryptase; HmMCP-3-like tryptase III; Mast cell mMCP-7-like; Tryptase-3 |
| Protein Family: | Tryptase |
| UniProt Gene Name: | TPSD1Â Â |
| UniProt Entry Name: | TRYD_HUMAN |
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