The TPPP Polyclonal Antibody (CAB8574) is a valuable tool for researchers studying the function of the TPPP protein in various biological processes. TPPP, also known as tubulin polymerization promoting protein, is involved in microtubule dynamics and has been implicated in neurodegenerative diseases such as Parkinson's and Alzheimer's.This polyclonal antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the TPPP protein, this antibody enables accurate detection and analysis in different cell types, making it an ideal choice for studies in neuroscience and neurology.
Understanding the role of TPPP in microtubule dynamics and its potential implications in neurodegenerative disorders is crucial for developing targeted therapies and treatment strategies. The TPPP Polyclonal Antibody provides researchers with a reliable tool for investigating the function and regulation of TPPP in various cellular processes, paving the way for new insights and discoveries in the field of neurobiology.
Product Name:
TPPP/p25 Rabbit Polyclonal Antibody
SKU:
CAB8574
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human TPPP/p25 (NP_008961.1).
Enables several functions, including GTPase activity; magnesium ion binding activity; and protein homodimerization activity. Involved in several processes, including microtubule cytoskeleton organization; negative regulation of tubulin deacetylation; and positive regulation of protein polymerization. Located in several cellular components, including mitochondrion; mitotic spindle; and perinuclear region of cytoplasm. Colocalizes with microtubule and microtubule bundle.
Purification Method:
Affinity purification
Gene ID:
11076
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TPPP/p25 antibody (CAB8574) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
