The TPP2 Polyclonal Antibody (CAB6421) is a powerful research tool specifically designed for studies involving TPP2, a key enzyme involved in protein degradation and cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the TPP2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for investigations in biochemistry and molecular biology.TPP2, also known as tripeptidyl peptidase II, plays a crucial role in protein turnover and degradation, impacting various cellular functions and pathways.
Its involvement in processes such as protein quality control and antigen processing highlights its importance in cell biology and immunology research. By delving into the mechanisms and function of TPP2, scientists can gain insights into its role in diseases such as neurodegenerative disorders, cancer, and metabolic syndromes, paving the way for targeted therapeutic interventions and drug development.
Product Name:
TPP2 Rabbit Polyclonal Antibody
SKU:
CAB6421
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TPP2 (NP_003282.2).
This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.
Purification Method:
Affinity purification
Gene ID:
7174
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TPP2 antibody (CAB6421) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
