TPP1 Rabbit Polyclonal Antibody (CAB5627)
- SKU:
- CAB5627
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TPP1 Rabbit Polyclonal Antibody |
SKU: | CAB5627 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human TPP1 (NP_000382.3). |
Sequence: | GANI STWV YSSP GRHE GQEP FLQW LMLL SNES ALPH VHTV SYGD DEDS LSSA YIQR VNTE LMKA AARG LTLL FASG DSGA GCWS VSGR HQFR PTFP ASSP YVTT VGGT SFQE PFLI TNEI VDYI SGGG FSNV FPRP SYQE EAVT KFLS SSPH LPPS SYFN ASGR AYPD VAAL SDGY WVVS NRVP IPWV SGTS ASTP VFGG ILSL INEH RILS GRPP LGFL NPRL YQQH GAGL FDVT RGCH ESCL DEEV EGQG FCSG PGWD PVTG WGTP NFPA LLKT LLNP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CLN2; GIG1; LPIC; SCAR7; TPP-1; TPP1 |
Positive Sample: | BT-474,SW480 |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome, Melanosome. |
Calculated MW: | 61kDa |
Observed MW: | 50kDa |
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Purification Method: | Affinity purification |
Gene ID: | 1200 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |