TPM3 Rabbit Polyclonal Antibody (CAB1206)
- SKU:
- CAB1206
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TPM3 Rabbit Polyclonal Antibody |
SKU: | CAB1206 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human TPM3 (NP_689476.2). |
Sequence: | MMEA IKKK MQML KLDK ENAL DRAE QAEA EQKQ AEER SKQL EDEL AAMQ KKLK GTED ELDK YSEA LKDA QEKL ELAE KKAA DAEA EVAS LNRR IQLV EEEL DRAQ ERLA TALQ KLEE AEKA ADES ERGM KVIE NRAL KDEE KMEL QEIQ LKEA KHIA EEAD RKYE EVAR KLVI IEGD LERT EERA ELAE SKCS ELEE ELKN VTNN LKSL EAQA EKYS QKED KYEE EIKI LTDK LKEA ETRA EFAE RSVA KLEK TIDD LEDE LYAQ KLKY KAIS EELD HALN DMTS I |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | TM3; TM5; TRK; CFTD; NEM1; TM-5; TM30; CAPM1; CMYP4A; CMYP4B; TM30nm; TPM3nu; TPMsk3; hscp30; HEL-189; HEL-S-82p; OK/SW-cl.5; TPM3 |
Positive Sample: | Mouse skeletal muscle,Mouse heart,Rat skeletal muscle,Rat heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cytoskeleton. |
Calculated MW: | 33kDa |
Observed MW: | 38-40kDa |
This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7170 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |