The TPM2 Polyclonal Antibody (CAB3096) is a valuable tool for researchers studying the TPM2 protein, which plays a key role in regulating muscle contraction and cell shape. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the TPM2 protein, this antibody enables the detection and analysis of TPM2 in various cell types, making it ideal for studies in muscle biology, cell physiology, and cardiovascular research.
TPM2, also known as tropomyosin beta chain, is essential for the proper function of muscle cells and is involved in maintaining muscle structure and contraction. Dysregulation of TPM2 has been linked to muscle diseases and cardiac disorders, making it a promising target for therapeutic interventions. Studying the role of TPM2 can provide valuable insights into muscle function and disease mechanisms, leading to the development of potential treatments for muscle-related disorders.
Product Name:
TPM2 Rabbit Polyclonal Antibody
SKU:
CAB3096
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TPM2 (NP_003280.2).
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7169
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TPM2 Rabbit pAb (CAB3096) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
