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TPH2 Rabbit Polyclonal Antibody (CAB14520)

SKU:
CAB14520
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TPH2 Rabbit Polyclonal Antibody
SKU:CAB14520
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-70 of human TPH2 (NP_775489.2).
Sequence:FDPK TTCL QECL ITTF QEAY FVSE SFEE AKEK MRDF AKSI TRPF SVYF NPYT QSIE ILKD TRSI ENVV QD
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:NTPH; ADHD7; TPH2
Positive Sample:NTERA-2,Mouse brain
Conjugate:Unconjugated
Cellular Localization:cytosol, neuron projection
Calculated MW:56kDa
Observed MW:52-56kDa

This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Purification Method:Affinity purification
Gene ID:121278
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using TPH2 Rabbit pAb (CAB14520) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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