The TPD52L2 Polyclonal Antibody (PAC020739) is a valuable tool for research involving TPD52L2, a protein associated with tumorigenesis and cancer progression. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the TPD52L2 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies in oncology and cancer research.TPD52L2, also known as tumor protein D54, plays a crucial role in various cellular processes related to cancer, including cell proliferation, migration, and invasion.
Its involvement in tumorigenesis and metastasis highlights its potential as a therapeutic target for the development of new cancer treatments. Understanding the function and regulation of TPD52L2 is essential for advancing our knowledge of cancer biology and identifying novel strategies for combating this disease.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20739(TPD52L2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-3: Mouse bladder tissue, K562 cells, MCF7 cells, Primary antibody: PACO20739(TPD52L2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute.
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20739(TPD52L2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12.
Synonyms:
tumor protein D52-like 2
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Aug 2011]
