The TPBG Polyclonal Antibody (CAB14790) is a valuable tool for researchers studying the trophoblast glycoprotein (TPBG), a cell surface protein associated with pregnancy and cancer. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TPBG protein, this antibody allows for the detection and analysis of TPBG in various cell types, making it ideal for investigations in reproductive biology and oncology research.
TPBG is known to play a crucial role in promoting cell growth and invasion, making it a potential target for cancer therapy. Additionally, its involvement in pregnancy-related processes suggests its importance in reproductive health and development. Research on TPBG using the CAB14790 antibody may provide valuable insights into the mechanisms underlying these processes, leading to the development of novel therapeutic strategies for both cancer and reproductive disorders.
Product Name:
5T4 Rabbit Polyclonal Antibody
SKU:
CAB14790
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 32-350 of human 5T4 (NP_006661.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
46kDa
Observed MW:
46kDa
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.
Purification Method:
Affinity purification
Gene ID:
7162
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using 5T4 Rabbit pAb (CAB14790) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
