The TP53RK Polyclonal Antibody (CAB14952) is a vital tool for researchers studying TP53RK, a protein involved in the regulation of cell cycle progression and DNA damage response. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the TP53RK protein, this antibody allows for the detection and analysis of TP53RK expression in various cell types, making it an essential tool for studies in cancer biology and DNA repair mechanisms.TP53RK plays a crucial role in maintaining genomic stability and cell integrity by regulating the activity of tumor suppressor p53 and other key proteins involved in DNA repair pathways.
Dysregulation of TP53RK has been linked to cancer development and progression, making it a promising target for the development of novel cancer therapies. By understanding the function and regulation of TP53RK, researchers can gain valuable insights into the molecular mechanisms underlying cancer growth and identify new strategies for targeted cancer treatment.
Product Name:
TP53RK Rabbit Polyclonal Antibody
SKU:
CAB14952
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TP53RK (NP_291028.3).
Enables p53 binding activity and protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in cytoplasm and nucleus. Part of EKC/KEOPS complex. Implicated in Galloway-Mowat syndrome 4.
Purification Method:
Affinity purification
Gene ID:
112858
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TP53RK Rabbit pAb (CAB14952) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
