The TP53I11 Polyclonal Antibody (CAB12855) is a valuable tool for research involving the TP53I11 protein, which is involved in DNA damage response and cell cycle regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to TP53I11, this antibody enables precise detection and analysis of the protein in various cell types, making it a valuable asset for studies in molecular biology and cancer research.TP53I11, also known as tumor protein p53-induced protein 11, is a key player in the p53 signaling pathway, which is crucial for maintaining genomic stability and preventing tumor formation.
Dysregulation of TP53I11 has been linked to cancer development and progression, making it a promising target for therapeutic intervention. Research into the function and regulation of TP53I11 is essential for developing targeted treatments that exploit its role in cancer biology.Overall, the TP53I11 Polyclonal Antibody is a reliable tool for investigating the role of TP53I11 in cellular processes and disease pathways, offering valuable insights that could lead to new therapeutic strategies for cancer and other related disorders.
Product Name:
TP53I11 Rabbit Polyclonal Antibody
SKU:
CAB12855
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human TP53I11 (NP_001245249.1).
Sequence:
MAAK QPPP LMKK HSQT DLVS RLKT RKIL GVGG EDDD GEVH RSKI SQVL GNEI KFTI REPL GLRV WQFV SA
Tested Applications:
WBIHC-PELISA
Recommended Dilution:
WB,1:500 - 1:1000 IHC-P,1:50 - 1:100
Synonyms:
PIG11; TP53I11
Positive Sample:
Mouse brain,Mouse heart
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Multi-pass membrane protein.
Calculated MW:
21kDa
Observed MW:
21kDa
Predicted to be involved in negative regulation of cell population proliferation. Predicted to be integral component of membrane.
Purification Method:
Affinity purification
Gene ID:
9537
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TP53I11 Rabbit pAb (CAB12855) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
