The TP53AIP1 Polyclonal Antibody (CAB7224) is specifically designed for research involving TP53AIP1, a protein also known as TP53-regulated inhibitor of apoptosis 1. This antibody is raised in rabbits and has high reactivity with human samples, making it suitable for a variety of research applications.TP53AIP1 is a key regulator of apoptosis, the process of programmed cell death, and is involved in various cellular processes related to cancer development and progression. With this antibody, researchers can detect and analyze TP53AIP1 expression in different cell types, providing valuable insights for studies in oncology and cell biology.
By targeting TP53AIP1, researchers can gain a better understanding of how this protein influences apoptosis and cell survival, shedding light on potential therapeutic strategies for cancer treatment. This antibody is validated for use in techniques such as Western blotting, enabling precise and reliable detection of TP53AIP1 in experimental settings.
Product Name:
TP53AIP1 Rabbit Polyclonal Antibody
SKU:
CAB7224
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human TP53AIP1 (NP_001238893.1).
This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
63970
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TP53AIP1 antibody (CAB7224) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
