The Torsin 1A Polyclonal Antibody (CAB2066) is specifically designed for researchers studying Torsin 1A, a protein associated with dystonia, a neurological movement disorder. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to Torsin 1A, this antibody allows for the detection and analysis of the protein in various cell types, making it a valuable tool for studies focused on understanding the role of Torsin 1A in neurological disorders.Torsin 1A is known for its involvement in maintaining cellular functions and has been linked to the development of dystonia, a condition characterized by involuntary muscle contractions.
By studying Torsin 1A, researchers aim to unravel the mechanisms underlying dystonia and potentially uncover new treatment strategies for this debilitating disorder. The Torsin 1A Polyclonal Antibody offers researchers a reliable means of investigating the function and expression of Torsin 1A, ultimately contributing to the advancement of neurological research and the development of targeted therapies for dystonia.
Product Name:
TOR1A Rabbit Polyclonal Antibody
SKU:
CAB2066
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 63-332 of human TorsinA/TOR1A (NP_000104.1).
The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1.
Purification Method:
Affinity purification
Gene ID:
1861
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TorsinA/TOR1A Rabbit pAb (CAB2066) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
