TOPBP1 Rabbit Polyclonal Antibody (CAB5781)
- SKU:
- CAB5781
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | TOPBP1 Rabbit Polyclonal Antibody |
SKU: | CAB5781 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1253-1522 of human TOPBP1 (NP_008958.2). |
Sequence: | KIIT IEET HEEL KKQY IFQL SSLN PQER IDYC HLIE KLGG LVIE KQCF DPTC THIV VGHP LRNE KYLA SVAA GKWV LHRS YLEA CRTA GHFV QEED YEWG SSSI LDVL TGIN VQQR RLAL AAMR WRKK IQQR QESG IVEG AFSG WKVI LHVD QSRE AGFK RLLQ SGGA KVLP GHSV PLFK EATH LFSD LNKL KPDD SGVN IAEA AAQN VYCL RTEY IADY LMQE SPPH VENY CLPE AISF IQNN KELG TGLS QKRK APTE KNKI KRPR VH |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Synonyms: | Dpb11; TOP2BP1; TOPBP1 |
Positive Sample: | HCT116 |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, spindle pole. |
Calculated MW: | 171kDa |
Observed MW: | 200kDa |
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.
Purification Method: | Affinity purification |
Gene ID: | 11073 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |