TOP3A Rabbit Polyclonal Antibody (CAB16987)
- SKU:
- CAB16987
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TOP3A Rabbit Polyclonal Antibody |
SKU: | CAB16987 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TOP3A (XP_011522303.1). |
Sequence: | MILA RNYL DVYP YDHW SDKI LPVY EQGS HFQP STVE MVDG ETSP PKLL TEAD LIAL MEKH GIGT DATH AEHI ETIK ARMY VGLT PDKR FLPG HLGM GLVE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TOP3; PEOB5; ZGRF7; MGRISCE2; TOP3A |
Positive Sample: | Mouse testis |
Cellular Localization: | mitochondrial matrix, nucleoplasm, nucleus, PML body |
Calculated MW: | 112kDa |
Observed MW: | 112kDa |
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 7156 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |