TONSL Rabbit Polyclonal Antibody (CAB13035)
- SKU:
- CAB13035
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | TONSL Rabbit Polyclonal Antibody |
SKU: | CAB13035 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-390 of human TONSL (NP_038460.4). |
Sequence: | MRTR LYLN LGLT FESL QQTA LCND YFRK SIFL AEQN HLYE DLFR ARYN LGTI HWRA GQHS QAMR CLEG AREC AHTM RKRF MESE CCVV IAQV LQDL GDFL AAKR ALKK AYRL GSQK PVQR AAIC QNLQ HVLA VVRL QQQL EEAE GRDP QGAM VICE QLGD LFSK AGDF PRAA EAYQ KQLR FAEL LDRP GAER AIIH VSLA TTLG DMKD HHGA VRHY EEEL RLRS GNVL EEA |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 |
Synonyms: | IKBR; SEMDSP; NFKBIL2; TONSL |
Positive Sample: | HeLa,Rat spleen,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 151kDa |
Observed MW: | 151kDa |
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
Purification Method: | Affinity purification |
Gene ID: | 4796 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |