The TOMM40 Polyclonal Antibody (CAB3213) is a valuable tool for researchers studying the TOMM40 protein, a key player in mitochondrial biology and Alzheimer's disease research. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for Western blot applications. By targeting the TOMM40 protein, researchers can effectively analyze and detect its expression in various cell types.TOMM40, also known as the Translocase of Outer Mitochondrial Membrane 40, is crucial for mitochondrial protein import and function, making it a vital component of cellular energy production and metabolism. Recent studies have identified TOMM40 as a potential biomarker for Alzheimer's disease, linking its dysfunction to the progression of this neurodegenerative disorder.
By studying TOMM40 expression and activity, researchers can gain valuable insights into mitochondrial dysfunction and its role in neurodegenerative diseases.With its ability to specifically target the TOMM40 protein, the CAB3213 antibody is an essential tool for investigating the role of TOMM40 in mitochondrial biology and neurodegenerative disorders. Its versatility and reliability make it a valuable asset for researchers interested in unraveling the complexities of Alzheimer's disease and mitochondrial dysfunction.
Product Name:
TOMM40 Rabbit Polyclonal Antibody
SKU:
CAB3213
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human TOMM40 (NP_001122389.1).
The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10452
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TOMM40 antibody (CAB3213) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
