The TOMM34 Polyclonal Antibody (CAB4467) is a valuable tool for researchers studying TOMM34, a protein involved in mitochondrial import and metabolism. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in applications such as Western blotting. By specifically binding to the TOMM34 protein, this antibody enables researchers to detect and analyze TOMM34 expression in various cell types, making it an essential component for studies in mitochondrial biology and metabolism research.TOMM34 is a key player in the import of proteins into mitochondria, crucial for maintaining proper mitochondrial function and cellular energy production.
Dysregulation of TOMM34 has been implicated in various diseases, including neurodegenerative disorders and cancer. Understanding the function and regulation of TOMM34 is critical for advancing our knowledge of mitochondrial biology and developing targeted therapies for related diseases.Overall, the TOMM34 Polyclonal Antibody is a valuable tool for researchers seeking to unravel the role of TOMM34 in mitochondrial function and its impact on health and disease. Its high specificity and reactivity make it an essential reagent for studies in mitochondrial biology, metabolism, and disease research.
Product Name:
TOMM34 Rabbit Polyclonal Antibody
SKU:
CAB4467
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human TOMM34 (NP_006800.2).
The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein, which is found in the cytoplasm and sometimes associated with the outer mitochondrial membrane, has a weak ATPase activity and contains 6 TPR repeats.
Purification Method:
Affinity purification
Gene ID:
10953
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TOMM34 Rabbit pAb (CAB4467) at 1:800 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 45s.