The TOMM22 Polyclonal Antibody (CAB14548) is a crucial tool for researchers studying TOMM22, a key protein involved in mitochondrial import and assembly. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the TOMM22 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in the fields of cell biology and metabolism.TOMM22, also known as translocase of outer mitochondrial membrane 22, plays a vital role in the import of proteins into mitochondria, an essential process for mitochondrial function and cellular metabolism.
Dysfunction in TOMM22 has been linked to mitochondrial disorders and neurodegenerative diseases, making it a target of interest for researchers investigating these conditions. By understanding the function of TOMM22, researchers can gain insights into mitochondrial biology and potentially develop targeted therapies for related diseases.
Product Name:
TOMM22 Rabbit Polyclonal Antibody
SKU:
CAB14548
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human TOMM22 (NP_064628.1).
The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion.
Purification Method:
Affinity purification
Gene ID:
56993
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TOMM22 Rabbit pAb (CAB14548) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
