The TOM70 Polyclonal Antibody (CAB4349) is a valuable tool for researchers studying the TOM70 protein, a key component of the translocase of the outer mitochondrial membrane complex. This antibody is produced in rabbits and is highly specific for detecting TOM70 in human samples, making it ideal for use in Western blot applications.The TOM70 protein plays a crucial role in mitochondrial protein import, serving as a receptor for precursor proteins targeted to the mitochondria. By binding to TOM70, this antibody enables researchers to detect and analyze the protein in various cell types, facilitating studies in mitochondrial biology, cell metabolism, and the role of mitochondria in disease states.
The TOM70 Polyclonal Antibody is essential for understanding the function and regulation of TOM70 in mitochondrial protein import pathways. With its high sensitivity and specificity, this antibody is an invaluable tool for researchers investigating mitochondrial dysfunction in conditions such as neurodegenerative diseases, metabolic disorders, and cancer.
Product Name:
TOM70 Rabbit Polyclonal Antibody
SKU:
CAB4349
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 245-608 of human TOM70 (NP_055635.3).
This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins. The protein interacts with the SARS-CoV and SARS-Cov-2 ORF9b proteins.
Purification Method:
Affinity purification
Gene ID:
9868
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TOM70 Rabbit pAb antibody (CAB4349) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
