The TOM70 Monoclonal Antibody (CAB21210) is a valuable tool for researchers studying the TOM70 protein, a component of the translocase of the outer mitochondrial membrane (TOM) complex involved in protein import into mitochondria. This antibody, produced using hybridoma technology, specifically recognizes TOM70 in human samples and is validated for use in applications such as Western blot and immunofluorescence.TOM70 is essential for mitochondrial protein import and plays a crucial role in maintaining mitochondrial function and cell viability. Dysregulation of TOM70 has been implicated in various diseases, including neurodegenerative disorders and metabolic syndromes.
This makes the TOM70 Monoclonal Antibody an important resource for investigating the role of TOM70 in mitochondrial biology and its implications for disease pathology.Researchers in the fields of cell biology, biochemistry, and mitochondrial research will find the TOM70 Monoclonal Antibody to be a reliable tool for studying the function and regulation of TOM70 in health and disease. Its high specificity and sensitivity make it an ideal choice for experiments aimed at understanding the molecular mechanisms underlying mitochondrial protein import and its impact on cellular homeostasis.
Product Name:
TOM70 Monoclonal Antibody
SKU:
CAB21210
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 245-608 of human TOM70 (NP_055635.3).
This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins. The protein interacts with the SARS-CoV and SARS-Cov-2 ORF9b proteins.
Purification Method:
Affinity purification
Gene ID:
9868
Clone Number:
ARC53258
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using TOM70 Rabbit mAb (CAB21210) at1:1800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
