The TOM1 Polyclonal Antibody (CAB9273) is a valuable tool for research involving TOM1, a protein involved in intracellular trafficking and protein sorting. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blotting.TOM1, also known as target of Myb1, plays a critical role in regulating protein trafficking and sorting within cells. By binding specifically to the TOM1 protein, this antibody enables accurate detection and analysis in a variety of cell types.
This makes it an ideal tool for studies in molecular biology and cell biology, particularly in the context of intracellular transport pathways and protein localization.Understanding the function of TOM1 is essential for unraveling its role in cellular processes such as endocytosis, autophagy, and protein degradation. By studying TOM1, researchers can gain insights into fundamental cellular mechanisms and potentially uncover new therapeutic targets for diseases related to dysregulated protein trafficking.
Antibody Name:
Anti-TOM1 Antibody
Antibody SKU:
CAB9273
Antibody Size:
20uL, 50uL, 100uL
Application:
WB IHC IF
Reactivity:
Human, Mouse, Rat
Host Species:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 314-493 of human TOM1 (NP_001129204.1).
This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Summary:
This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Homo sapiens target of myb1 membrane trafficking protein (TOM1), transcript variant 1, mRNA
NCBI Synonym Full Names:
target of myb1 membrane trafficking protein
NCBI Official Symbol:
TOM1Â Â
NCBI Protein Information:
target of Myb protein 1
UniProt Protein Name:
Target of Myb protein 1
Protein Family:
TOM1-like protein
UniProt Gene Name:
TOM1Â Â
UniProt Entry Name:
TOM1_HUMAN
Western blot analysis of extracts of various cell lines, using TOM1 antibody (CAB9273) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Immunofluorescence analysis of 293T cells using TOM1 antibody (CAB9273) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
