The Tollip Polyclonal Antibody (CAB2202) from Assay Genie is a valuable tool for researchers studying Tollip, an important regulator of Toll-like receptor signaling. Tollip is known to interact with various proteins involved in innate immune responses, making it a key player in the immune system's defense against pathogens.This polyclonal antibody is produced in rabbits and has been validated for use in Western blot applications. It specifically binds to Tollip protein, allowing for detection and analysis in a variety of cell types. Researchers studying immunology, infectious diseases, and inflammatory conditions will find this antibody essential for their investigations.
By understanding the role of Tollip in regulating immune signaling pathways, researchers can gain insights into how the immune system responds to infections and inflammatory stimuli. This knowledge may lead to the development of targeted therapies for conditions where immune dysregulation plays a significant role. The Tollip Polyclonal Antibody is a powerful tool for advancing research in this field.
Product Name:
TOLLIP Rabbit Polyclonal Antibody
SKU:
CAB2202
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human TOLLIP (NP_061882.2).
This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
54472
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using TOLLIP Rabbit pAb (CAB2202) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
