TNXB Rabbit Polyclonal Antibody (CAB2535)
- SKU:
- CAB2535
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | TNXB Rabbit Polyclonal Antibody |
SKU: | CAB2535 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 444-673 of human TNXB (NP_115859.2). |
Sequence: | TSFT TGGL RIPF PRDC GEEM QNGA GASR TSTI FLNG NRER PLNV FCDM ETDG GGWL VFQR RMDG QTDF WRDW EDYA HGFG NISG EFWL GNEA LHSL TQAG DYSM RVDL RAGD EAVF AQYD SFHV DSAA EYYR LHLE GYHG TAGD SMSY HSGS VFSA RDRD PNSL LISC AVSY RGAW WYRN CHYA NLNG LYGS TVDH QGVS WYHW KGFE FSVP FTEM KLRP RNFR SPAG GG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | XB; TNX; XBS; EDS3; HXBL; TENX; TN-X; VUR8; TNXB1; TNXB2; TNXBS; EDSCLL; EDSCLL1; TNXB |
Positive Sample: | Mouse liver,Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 458kDa |
Observed MW: | 69kDa |
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7148 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |