The Tenascin-X Polyclonal Antibody (CAB2535) is a powerful tool for researchers studying the extracellular matrix protein, tenascin-X. This antibody, produced in rabbits, specifically targets tenascin-X and is highly reactive with human samples. Validated for use in Western blot applications, it allows for the detection and analysis of tenascin-X in a variety of cell types.Tenascin-X is a crucial component of the extracellular matrix, playing a key role in tissue development and wound healing. Aberrant expression of tenascin-X has been implicated in various diseases, including Ehlers-Danlos syndrome and certain types of cancer.
By using the Tenascin-X Polyclonal Antibody, researchers can further investigate the function and regulation of tenascin-X, potentially leading to new insights into disease mechanisms and potential therapeutic strategies.Overall, the Tenascin-X Polyclonal Antibody is a valuable tool for research in areas such as developmental biology, tissue engineering, and cancer biology. Its specificity and reliability make it an essential reagent for scientists seeking to unravel the intricate roles of tenascin-X in health and disease.
Product Name:
TNXB Rabbit Polyclonal Antibody
SKU:
CAB2535
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 444-673 of human TNXB (NP_115859.2).
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7148
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TNXB Rabbit pAb (CAB2535) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
