TNRC6A Rabbit Polyclonal Antibody (CAB6115)
- SKU:
- CAB6115
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | TNRC6A Rabbit Polyclonal Antibody |
SKU: | CAB6115 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 950-1050 of human TNRC6A (NP_055309.2). |
Sequence: | QDIV GSWG IPPA TGKP PGTG WLGG PIPA PAKE EEPT GWEE PSPE SIRR KMEI DDGT SAWG DPSK YNYK NVNM WNKN VPNG NSRS DQQA QVHQ LLTP ASAI S |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:100 |
Synonyms: | GW1; FAME6; GW182; TNRC6; CAGH26; TNRC6A |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, P-body. |
Calculated MW: | 210kDa |
Observed MW: | 180kDa |
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
Purification Method: | Affinity purification |
Gene ID: | 27327 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |