The TNRC6A Polyclonal Antibody (CAB6115) is a valuable tool for researchers studying TNRC6A, a key player in the RNA interference pathway. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to TNRC6A, the antibody allows for precise detection and analysis of this protein in various cell types, making it an ideal choice for studies in molecular biology and RNA regulation.TNRC6A, also known as trinucleotide repeat-containing gene 6A, is essential for the function of microRNAs and the silencing of target genes.
Its role in post-transcriptional gene regulation makes TNRC6A a crucial factor in processes such as development, cell differentiation, and disease pathogenesis. Researchers interested in understanding the intricacies of RNA interference and gene silencing will find the TNRC6A Polyclonal Antibody an indispensable tool for their studies.
Product Name:
TNRC6A Rabbit Polyclonal Antibody
SKU:
CAB6115
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 950-1050 of human TNRC6A (NP_055309.2).
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
Purification Method:
Affinity purification
Gene ID:
27327
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TNRC6A antibody (CAB6115) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
