The Transportin-1 Polyclonal Antibody (CAB9435) is a vital tool for research involving Transportin-1, a protein involved in nucleocytoplasmic transport of various molecules. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By targeting the Transportin-1 protein, this antibody enables researchers to study its role in the transport of macromolecules across the nuclear membrane in different cell types, making it an essential tool for studies in molecular biology and cell biology.Transportin-1 is a key player in the regulation of cellular processes such as gene expression, signal transduction, and protein transport.
Understanding the function of Transportin-1 is crucial for unraveling the mechanisms underlying cellular communication and regulation. Research on Transportin-1 has implications for various fields including cancer biology, neurodegenerative diseases, and viral infections. By using the Transportin-1 Polyclonal Antibody, researchers can gain valuable insights into the role of Transportin-1 in these processes, aiding in the development of targeted therapies and interventions.
Product Name:
TNPO1 Rabbit Polyclonal Antibody
SKU:
CAB9435
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 790-890 of human TNPO1 (NP_002261.3).
This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in several transcript variants encoding different proteins.
Purification Method:
Affinity purification
Gene ID:
3842
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TNPO1 antibody (CAB9435) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 1s.
