Cardiac troponin T (TNNT2) Rabbit Polyclonal Antibody (CAB1126)
The TNNT2 Polyclonal Antibody (CAB1126) is a vital tool for researchers studying the TNNT2 protein, which is essential for muscle contraction and cardiac function. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications, enabling accurate detection of TNNT2 in various cell types.TNNT2, also known as cardiac troponin T, is a key player in regulating muscle contraction in the heart.
Abnormalities in TNNT2 expression or function have been linked to various cardiovascular diseases, making it a crucial target for research in cardiology and cardiovascular physiology. By using the TNNT2 Polyclonal Antibody, researchers can study the expression and behavior of TNNT2 in both healthy and diseased tissues, leading to a better understanding of cardiac function and potential therapeutic targets for heart-related conditions.
Product Name:
Cardiac troponin T (TNNT2) Rabbit Polyclonal Antibody
SKU:
CAB1126
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Cardiac troponin T (Cardiac troponin T (TNNT2)) (NP_001001431.1).
This gene encodes the cardiac isoform of troponin T. The encoded protein is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy.
Purification Method:
Affinity purification
Gene ID:
7139
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Cardiac troponin T (TNNT2) antibody (CAB1126) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
