The TNNC2 Polyclonal Antibody (CAB7740) is a valuable tool for researchers investigating TNNC2, a protein involved in muscle contraction and calcium signaling. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By targeting the TNNC2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in muscle biology, cardiovascular research, and more.
TNNC2, also known as troponin C, plays a crucial role in regulating muscle contraction by binding calcium ions. Dysregulation of TNNC2 function has been linked to various muscle-related disorders, making it a key target for therapeutic interventions. Studying the expression and activity of TNNC2 can provide valuable insights into the mechanisms of muscle function and dysfunction, with implications for the development of treatments for muscle disorders and cardiovascular diseases.
Product Name:
TNNC2 Rabbit Polyclonal Antibody
SKU:
CAB7740
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TNNC2 (NP_003270.1).
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.
Purification Method:
Affinity purification
Gene ID:
7125
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TNNC2 Rabbit pAb (CAB7740) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 15s.
